Patients who are heavily intoxicated may show adverse reactions during the first few chelation treatments. The most common side effects noted are weakness during the day of chelation treatment, dull headaches and concentration difficulties. Some patients notice a slight decrease in vision ability, which will be gone the next day. Abdominal cramping may be experienced in patients with digestive problems. It is thus important to ‘detox’ the GI tract prior to oral chelation. Allergy reactions are rare, but can occur.
Depending on exposure and patient constitution, 10 to 30mg/kg per body weight are recommended. Oral chelators are preferably taken on an empty stomach. If possible, the patient should not eat for two hours following intake.
Pre-Chelation Treatment Recommendations:
Prior to Treatment:
Chelation treatment – Option A
(Night i.e. home treatment)
Before oral intake of DMSA, patient should empty bladder. This would be the baseline urine.*
Chelation treatment – Option B
*Baseline Urine (optional, but recommended for first treatment): The baseline urine is to be collected prior to the first chelation treatment. Required are 10ml of urine for testing. The baseline urine may be taken as a first morning specimen or prior to treatment as outlined above.
**Provocation urine: This sample is only taken every 3-4 month. Another baseline urine is not necessary, unless medical or environmental conditions warrant another test. The laboratory needs 10ml of each urine sample for testing.
For proper sample submission, see Patient Submission Sheet.