The number of amalgam fillings and dental alloys of 86 female patients were recorded. The salivary and urinary concentrations of mercury were determinated by atomic absorption spectrometry (AAS) and the concentrations of various metallic components (silver, copper, tin, gold, palladium, platinum, cobalt, molybdenum, indium, gallium) were analyzed by inductively coupled plasma mass spectrometry (ICP-MS). The saliva concentrations of mercury were also determinated after chewing gum and the urinary concentrations of mercury and tin 45 minutes after application of 250 mg DMPS (dimercaptopropane sulfonate). The salivary concentrations of mercury, silver, tin and the urinary mercury excretion after DMPS correlated significantly with the number of amalgam fillings, In contrast, there was an inverse significantly correlation between the urinary tin excretion after DMPS and the number of amalgam fillings; also between the urinary tin after DMPS and mercury in saliva before chewing. Possibly there are competitive interactions between the urinary excretion of mercury and tin. Dental alloys shows no effects of the mercury release from dental amalgam. Presumable oral galvanic elements do not exist. Our results showed, that the urinary excretion of metals before DMPS is unsuitable to value the metal burden due to amalgam fillings and dental alloys.
umwelt-medizin-gesellschaft 17 (1): 57-67
Authors: Prof. Dr. med. Ingrid Gerhard, Universitäts-Frauenklinik Heidelberg, Dep. f. Gynäkologische Endokrinologie und Fertilitätsstörungen, Ambulanz für Naturheilkunde, Voßstr. 9, 69115 Heidelberg; Claudia Ganzer, Palmersdorfer Hof 16, D-50321 Brühl